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November 01, 2006

MoleculeRole Ontology Ver.2.20

The latest MoleculeRole Ontology is Ver2.20

MoleculeRole Ontology is an ontology for proteins.

You can download it from the OBO site and from our download page.

Statistics
==========
All entries 8457
Chemicals 592
Proteins 7864
Obsoletes 23

UniProt ACs 5286
GO IDs 322
InterPro ACs 32
KEGG COMPOUND IDs 587
PubMed IDs 78

MoleculeRole Ontology Release Notes
=====================
Version: 2.20 (Nov 1, 2006)

Molecule Role is a hierarchical ontology which contains the molecular functional group names, the abstract molecule names and the concrete molecule names collected from literature manually. This classification is based on a conceptual classification of molecular roles in protein interaction and signal transduction.

Changes from version 2.1x
=====================
KEGG metabolic pathway related molecules (500~ chemicals and 300~ proteins) were added.

Changes from version 2.0x
=====================
Over 13,000 synonyms were added from EntrezGene, HGNC, FlyBase, OMIM, MGI and RGD database in an automatic way, using UniProt ACs manually collected in Molecule Role.

Changes from version 1.xx
=====================
The ontologies and definitions are provided together in a single OBO format flat file. This data is NOT also available in the GO flat file format as an ontology file and a definitions file.

Protein sequences (=UniProt ACs) in the DbXrefs of protein leaf-class entries have been separated as new protein leaf-class entries. The parents-children relationship type is "sequence_of". The relationships of "Concrete-Names (e.g. ERK1)" and protein sequences (e.g. P27361) have been defined explicitly.

More information about MoleculeRole Ontology
---------------------
Satoko Yamamoto, Takao Asanuma, Toshihisa Takagi, Ken Ichiro Fukuda. The Molecule Role Ontology: an ontology for annotation of signal transduction pathway molecules in the scientific literature. Comparative and Functional Genomics 2004 Volume 5, Issue 6-7, p 528-536. (http://www3.interscience.wiley.com/cgi-bin/fulltext/109860932/HTMLSTART)


Statistics
==========
All entries 8457
Chemicals 592
Proteins 7864
Obsoletes 23

UniProt ACs 5286
GO IDs 322
InterPro ACs 32
KEGG COMPOUND IDs 587
PubMed IDs 78

Posted by SatokoYamamoto : 04:59 PM | TrackBacks